The Year in Review

The Year in Review offers a synoptic review of notable new literature in various sub-specialties of transgender care. Confirmed speakers are:

Dr. Fotis Papadopoulos

Mental health (adults)
The aim of this Year in Review on mental health is to provide a synoptic review of notable recent literature on mental health in transgender care, with a particular focus on studies relevant to healthcare decision-making. A systematic search was conducted in PubMed covering the period from January 2023 to August 2025, using keywords related to mental health in transgender and gender diverse populations. A total of 1,264 articles were screened at the title and abstract level. Selected articles were reviewed in full and categorized into the following themes: Mental health disparities, Mental health outcomes associated with gender-affirming treatments, Outcome measures, Healthcare systems and access to care, Psychological interventions, and Detransition and regret. Seminal articles from each theme will be briefly presented. 
Bio
Dr. Fotis Papadopoulos (he/his) is a Professor of Psychiatry at the Department of Medical Sciences, Uppsala University, Sweden, and a practicing psychiatrist at the Gender Identity Clinic at Uppsala University Hospital. He chairs the Swedish national quality register for gender dysphoria and leads multiple national research initiatives, including a multicenter cohort study on gender dysphoria, a qualitative study on detransition, and the development of a core outcome set for gender-affirming treatment. His research focuses on treatment outcomes in gender dysphoria, with an emphasis on gender incongruence, body satisfaction, mental health, and treatment side effects. Dr. Papadopoulos also chairs Sweden’s national working group in research in gender dysphoria including an initiative for a national research network on gender dysphoria.

Dr. Dagmar Pauli

Mental health (children & adolescents)
Mental Health in Adolescents with Gender Incongruence 

There is a growing body of evidence about mental health impairments in transgender youth and about the course of mental health problems in adolescents recieving gender affirming care. Cross sectional studies from many countries indicate high rates of depression, suicidal ideation and self harm as well as anxiety disorders and eating disorder symptoms in transgender youths. The majority of the studies show higher rates of mental health impairments in trans adolescents assigned male at birth compared to those assigned female at birth. Recent studies including the examination of non-binary identities show a particularly high rate of psychopathological symptoms in this group. In addition, studies with adolescents seeking gender affirming care as well as samples from autism consultations report a high coincidence rate of autism and gender incongruence. However, there seems to be a subgroup of trans youths that do not show accompanying mental health impairments. Protective factors derived from studies inculde support from family members and peers, and – with limited evidence – social transition and medical gender affiming care. 

Longitudinal studies examining the course of mental health impairments and well-being in trans youths recieving medical gender affirming care suggest that mental health impairments appear to improve over time, but evidence is still scarce. Recent reviews show moderate evidence for the positive effects of treatment with gender affirming hormones on psychopathological impairment in minors. The effects of puberty blocking on mental health aim at stablizing the young person in a difficult time of the decision-making process, although the evidence to date is limited. The ongoing debate about the level of evidence and mixed cloncusions drawn from the available literature emphasize the need for further long-term longitudinal studies of this vulnerable population. 

Bio
Dagmar Pauli is medical doctor and a specialist in child and adolescent psychiatry. She is Chief Physician and Deputy Director of the Child and Adolescent Psychiatry Department at the Psychiatric University Hospital Zurich. Her clinical and research specialties are eating disorders, depression and gender incongruence in children and adolescents. In 2009, she founded the first outpatient unit for children and adolescents with gender incongruence in Switzerland and has been actively involved in this topic in clinical practice and research ever since. She was delegated by the Swiss Society for Child and Adolescent Psychiatry to participate in the guideline group of the Association of the Swiss Medical Societies AWMF for the development of the new guidelines for the treatment of gender incongruence and gender dysphoria in children and adolescents for Germany, Austria and Switzerland.

Dr. Sabine Hannema

Endocrinology
Bio
Sabine Hannema is paediatric endocrinologist at the Centre for Atypical Sex and Gender Development at Amsterdam UMC since 2020. She is board member of the Center of Expertise on Gender Dysphoria. Previously she was the endocrine lead of the gender clinic at Leiden University Medical Centre and worked in the DSD team at Erasmus University Medical Centre, Rotterdam. She received her PhD from Cambridge University, U.K. Her main areas of interest are DSD and transgender care. She is co-author of the Endocrine Society Clinical Practice Guideline ‘Endocrine Treatment of Gender-Dysphoric/Gender-Incongruent Persons’ and the Dutch Quality Standard for Transgender care.

Dr. Julia Bohr

Surgery
Background:
Gender affirming surgery is a desirable option for many people with gender incongruence. In recent years, the demand for and number of operations performed has steadily increased, as has the number of publications and techniques developed to provide those seeking treatment with the best possible options. Recently, however, changes in the political mood have led to a decline in social acceptance and treatment options in many places. It can be assumed that this makes it more difficult for patients to access surgical treatment options. 

Aim:
Review and evaluation of the literature in terms of innovation and accessibility for patients. 

Methods:
A literature search was carried out in the Pub Med database. Publication dates were set between February 2023 and June 2025. The main search terms were transgender and surgery. All original papers and reviews as well as case reports were included in the results, whereby only full-text papers in English language were accepted. 

Results:
A total of 1144 hits were obtained using the search function. Of these, 253 were (systematic) reviews, but only 9 were clinical studies. A total of 70 case reports were found.
The abstracts were screened and weighted and categorised according to their relevance to the research question. Irrelevant hits were removed.
The presentation will summarise the results and place them in context, both qualitatively and quantitatively. 

Bio
Julia Bohr (she/her) is head of the interdisciplinary Centre for Transgender surgery at the Kliniken Essen-Mitte, Germany. Trained as urologist, she is working in the field of surgical transgender care for more than 17 years.

She specializes in vaginoplasty, metoidioplasty, prosthetics and urethral reconstruction in the context of gender reassignment surgeries.

Julia is a member of WPATH and EPATH and a member of the transgender surgery working groups of the DGU (German Society of Urology) and the ESGURS (genito-urinary reconstructive section of the European Urological Association, EAU). Furthermore, she is co-author resp. co-coordinator of the interdisciplinary German guidelines on gender incongruence.

In addition to her clinical and surgical work, she also holds a qualification in subject-related psychotherapy.

Dr. David Doyle

Social & Political Sciences
The social and political sciences have perhaps never been more relevant to transgender healthcare as today in the context of growing societal polarization and increasing political interference in medicine across countries. This difficult situation is reflected in the title of a recent special issue of Social Science & Medicine (2024), ‘Unequal care: Trans medicine and health in dangerous times.’ Combining topics derived from this special issue alongside systematic searches of academic databases (Scopus, PsycINFO, Google Scholar) for articles published within the last two years (2023-2025), I identify key themes in research on transgender healthcare within the social and political sciences related to, for example: (gender) minority stress, structural stigma, anti-trans legislation, regional variations, mis/disinformation, community knowledge, biases in (education in) medicine, social support/affirmation, and intersectionality. As evidenced by these themes, healthcare practitioners and medical researchers need to work more closely with social and political scientists in these ‘dangerous times’ in order to better understand the influence of societal attitudes and broader social structures on healthcare access and outcomes for trans and gender diverse people. 
Bio
Dr. Doyle is a social psychologist by training with additional expertise in epidemiology, neuroendocrinology, and mental health. He is currently Assistant Professor in the Department of Medical Psychology at Amsterdam UMC. The concept of social health, having adequate quantity and quality of relationships in a particular context to meet an individual’s need for meaningful human connection, is an organizing focus of research in his group. He is currently investigating the potential psychosocial implications of gender-affirming hormone therapy for transgender people throughout the life course in the AFFIRM Relationships project, supported by a Starting Grant from the European Research Council (2023-2028). He is also coordinator of the Gender-InSIGHT doctoral network recently funded by an MSCA DN grant (2026-2030) to investigate biopsychosocial influences on gender during (diverse) hormonal transitions, with partners from both academic and non-academic sectors across Europe and main training sites in Amsterdam, Berlin, Copenhagen, and Oslo.

Dr. Florian Schneider

Reproductive health
Bio
Dr. Florian Schneider studied medicine in Witten, Cleveland and Cape Town. He is a paediatrician, neonatologist and diabetologist and currently works at the University of Münster in the Department of Paediatric Endocrinology and at the Centre of Reproductive Medicine and Andrology, mostly working with adolescents with gender incongruence. His research topics are: Influence of gender affirming hormone therapy and puberty blockers on different cell types in the (adult and adolescent) human testes, fertility preservation in (adult and adolescent) persons assigned male at birth, fertility preservation in persons with disorders of sex development and influence of comorbidities (i.e. T2D, arterial hypertension) on male reproduction. He has authored and co-authored numerous studies on these topics and he has been attending the EPATH conferences since the beginning.

Dr. Dominique Morsomme

Voice and communication
Background :
The capacity to shape and adapt vocal motor behavior according to individual preferences is at the core of transaffirmative voice care, an emerging interdisciplinary field that integrates
medical, psychological, communicative, and sociocultural perspectives. For transgender and gender-diverse individuals, the voice is a pivotal element in both the perception of their gender by others and their own processes of gender affirmation. The facilitation of a congruent and authentic vocal expression through individualized care is therefore essential. Contemporary approaches to vocal motor behaviour allow for its intentional modulation in accordance with personal preferences. Transaffirmative voice care increasingly strives to accommodate the unique identities of individuals, the evolving array of technical tools, and a
situated understanding of the communicative contexts in which voice is embodied and expressed. This presentation seeks to deliver a comprehensive synthesis of the literature on voice and communication within trans and non-binary populations, covering developments from the 2023 EPATH conference through to 2025.
Methods: This review included peer-reviewed journal articles, written in English and published between 2023 and 2025. Studies were eligible if they focused on the voice and communication of trans and non-binary adults. Three databases – Embase
(www.embase.com), Medline (Ovid), and Scopus (www.scopus.com) – were searched on 20 June 2025, using a combination of three key concepts (voice AND communication AND trans or non-binary people). The results were limited to the publication period covered by this
review. Covidence was used to manage the review process (from eliminating duplicates to extracting data from included studies). An expert in literature review methodology oversaw the process to ensure its rigor, while a subject-matter expert reviewed exclusions for accuracy. The included studies were grouped thematically. Data were presented in a narrative synthesis accompanied by graphic visualizations and tables.
Results: A total of 352 references were found in the three databases and 167 duplicates were removed. Of the 185 references screened based on title and abstract, 59 were excluded. Assessment of the 126 full texts based on eligibility criteria led to the inclusion of 103 journal articles (23 were excluded for the following reasons: non-English language (n = 8), non-peer reviewed journal articles (n = 14), and non-target populations (n = 1)). Eleven thematic areas were identified: autism, voice training, laryngeal surgery, assessment, epistemological reflection, professional training, technologies, general information, database, tobacco, and geographical reality. Nine of these themes included at least two studies and were therefore included in the synthesis, while themes represented by a single study were not synthesized. Recent developments in trans-affirmative vocal care (2023–2025) indicate a significant transformation in the field. Contemporary approaches increasingly prioritize care that is personalized to clients’ vocal goals and gender identity, grounded in rigorous scientific evidence, and enhanced by emerging technologies. As a key marker of identity, social recognition, and emotional well-being, the voice calls for individualized care that moves beyond binary models to embrace androgynous, fluid, or non-gendered vocal expressions. Empirical studies explore the benefits of voice therapy in supporting vocal congruence and
psychosocial well-being. Some studies also describe innovations – such as machine learning based tools, voice-centered apps and immersive virtual reality platforms – as promising avenues for enhancing therapeutic precision and engagement. Emerging frameworks further emphasize client-led goal setting and fluid trajectories over binary vocal norms. Studies also stress the need to raise awareness of vocal health professionals’ roles among both the public and patients, underscoring the importance of collaborative, well-informed care. Cross-cultural perspectives challenge Western-centric models, urging more context-sensitive practices. Moreover, research calls for inclusive, tailored care for trans and autistic individuals, centered on their lived experiences and specific needs, while highlighting the urgent need for clinical and educational frameworks that address both neurodiversity and gender diversity. Finally, it calls for enhanced training of professionals to provide trans-affirmative, reflective, and safe care.
Conclusions. Increasingly, voice therapy and surgery are integrated into holistic care pathways. These developments collectively support a more inclusive, pluralistic, and empowering model of vocal transition. As the field evolves, it underscores the importance of agency, diversity, and ethical responsiveness in trans vocal health.
Bio
Dominique Morsomme is a speech-language pathologist specialized in voice disorders, a vocologist, and an academic researcher. She began her clinical and academic career at the Saint-Luc University Clinics and the Catholic University of Louvain, before joining the University of Liège and the University Hospital of Liège. Since 2017, she has served as a full-time faculty member at the Faculty of Psychology, Speech Therapy, and Educational Sciences (FPLSE), where she directs the Voice Unit (ULV). In 2021, she assumed leadership of the RUCHE research unit (Research Unit for a life-Course perspective on Health and Education), which focuses on innovation in health and education, including the integration of emerging technologies.

 

Her research primarily focuses on the evaluation and optimization of oral communication, with particular attention to voice production and perception. Her doctoral work significantly advanced clinical standards by establishing acoustic and perceptual parameters for voice assessment that are now used in protocols adopted by Belgium’s National Institute for Health and Disability Insurance. Within the ULV, she continues to develop technology-enhanced approaches to vocal diagnostics and care.

For the past few years, one of her most dedicated areas of research has been trans-affirmative voice care for transgender individuals. From a perceptual perspective, she investigates how listeners perceive vocal gender, with a focus on the acoustic cues that signal it. From a production perspective, she examines how vocal motor behaviour can be effectively adapted to align with a person’s gender identity. This research requires both scientific rigor and humility, given the complexity of modifying biologically gendered vocal patterns to reflect a desired vocal gender.

In parallel, Dominique Morsomme is actively engaged in institutional efforts to promote gender equity. She is a member of the “Genre et Egalité” working group led by Professor Florence Caeymaex (Chair in Ethics and Medical Humanities) and co-founded the interdisciplinary group “Parole et Écriture” with writer Geneviève Damas. She collaborates on research projects with the Universities of Ghent, Grenoble, Marseille, Paris, and Montreal. While maintaining a strong academic profile, she also ensures regular clinical practice, notably through ongoing collaboration with Professor Camille Finck at the University Hospital of Liège.

Her broader research interests include voice disorders, vocal assessment, and the implementation of Evidence-Based Practice in speech-language pathology.

For more information :
ULV : www.vocologie.uliege.be
Publications: https://orbi.uliege.be/myorbi

Dr. Peter Dunne

Law, policy, and ethics

This presentation will explore both legal research, as well as legislative and case law developments, over the past two years – focusing on the intersections of gender identity, gender expression and law. With a particular interest for the fields of medical law and family law, the presentation will introduce attendees to a selection of monographs, edited collections, journal articles and reports, published since 2023, which address the legal rights and status of trans and non-binary people. In an area of substantial legislative and judicial activity, the presentation will also introduce key national and regional court judgments, and it will highlight a number of actual and proposed legal reforms. The presentation will focus primarily on Europe, but it will also draw from relevant academic resources and legal updates in other parts of the world. Ultimately, the presentation will offer attendees a concise, yet informative, overview of law-focused developments since the last EPATH conference.

Bio
Dr Peter Dunne is a Senior Lecturer at the University of Bristol Law School and an Associate Member of Garden Court Chambers. He is an expert in the field of LGBTI rights and the law. In 2022, Peter was awarded a multi-year research grant by UK Research and Innovation to explore the rights of trans and non-binary people in England and Europe. Peter has published extensively across a range of topics on LGBTI rights, including queer parenting, legal gender recognition and the rights of LGBTI children. He has worked extensively as an expert for the UK government, Scottish government, European Commission and institutions of the Council of Europe. He has also provided expert evidence on LGBTI rights to the UK and Scottish parliaments. Prior to entering academia, Peter worked as a human rights advocate in the United States and Europe. Peter is a graduate of UCD, Harvard Law School and the University of Cambridge.