In the light of partly inconsistent evidence the standards for best practice in transgender health care in adolescence are still a focus of international debate. In current treatment guidelines as developed by scientific medical societies, however, there is broad agreement in that appropriate healthcare in this field has to face these uncertainties just as this is the case in other complex conditions in paediatric medicine. Therefore practice guidelines are needed that are based on both the best available evidence and the broadest available clinical expert consent. Furthermore, guidelines should define how to address the ethical challenges in this field that arise from balancing beneficence and non-maleficence, and giving due weight to autonomy and justice. Furthermore, treatment recommendations should be particularly sensitive to aspects of participation and discrimination of this patient group representing a vulnerable minority. In this keynote, the following recently released practice guidelines and consensus papers from various European countries will be summarized and discussed with a focus on how they address the issues around evidence and ethics in this field:

 German S2k-guideline Gender Incongruence and Gender Dysphoria in Childhood and Adolescence: Diagnosis and Treatment, published by the German Association of Scientific Medical Societies (AWMF, 2024);
 Recommendation paper: Medical treatment for minors with gender dysphoria: Ethical and legal considerations, published by the Swiss National Advisory Commission on Biomedical Ethics (2024);
 Practice guideline: Endocrine management of transgender and gender diverse adolescents, Expert opinion of the ESPE Working Group on Gender Incongruence (2024):
 Practice guideline: Endocrine management of transgender adolescents: Expert consensus of the french society of pediatric endocrinology and diabetology working group (2024)

Tuisina Ymania Brown MBA LL.M. MIPL
She/Her | Trans | Fa’afafine
Berlin | Brisbane | Wellington | Samoa
Global Trans Leader

Ymania Brown is a proud fa’afafine and trans woman from Samoa who has survived and risen through some of the harshest realities of transphobia, violence, employment discrimination, and domestic abuse.
A former intellectual property lawyer with an MBA, LLM. and a Masters in Intellectual Property Law, she over two decades in corporate Australia across finance, HR, and legal sectors, she now dedicates her life to advancing global human rights.
Ymania is a single mother to legally adopted sons and brings over 20 years of executive leadership in international NGOs. Her work bridges LGBTIQ rights, Indigenous justice, interfaith inclusion, environmental protection, and economic equity.
She currently serves as Executive Director of TGEU (Transgender Europe) and Co-President of InterPride, bringing a strategic global lens to governance, policy, funding, and risk management.
Her previous leadership includes roles as Co-Secretary General of ILGA World, Advisory Board Member at Astraea Lesbian Foundation for Justice (New York), Co-Chair of the International Trans Fund (Toronto), Co-Chair of the Global Interfaith Network (GINSSOGIE) (Johannesburg), and International Advisory Board Member for WorldPride Copenhagen 2021.
Deeply grounded in her First Nations Samoan heritage, Ymania holds four chiefly titles across Samoa and is a powerful voice at the intersection of trans rights, indigenous sovereignty, spirituality and faith, climate justice, and human rights.

Dr. Adrian Hector is a prominent advocate for gender diversity and inclusion. He studied and earned his PhD in physics across Hamburg, Paris, and Cambridge.

A committed activist, Dr. Hector has held leadership roles in several LGBTQ+ organizations, including serving as executive board member of the Bundesverband Trans* from 2018 to 2019. He has been active in politics with the German Green Party (BÜNDNIS 90/DIE GRÜNEN) since 2018, where he has served in various capacities, including as spokesperson for QueerGrün Hamburg and deputy spokesperson for the federal working group on gay policy.

Since 2022, he has been a member of the Hamburg Parliament, where he is the spokesperson for gender diversity, science, and higher education. His political work focuses on dismantling structural discrimination, promoting self-determination laws, and advancing inclusive policies in education and public life.

Dr. Hector is a trans man who came out five years ago, and his personal journey has deeply informed his advocacy. He organizes peer support groups for trans men and non-binary individuals and champions reforms to Germany’s legal and healthcare systems to better serve trans communities.